Two Synchronous Neonatal Tumors: An Extremely Rare Case
| Autor: | A. San Roman, C. Lagues, K. Albarenque, C. Schauvinhold, M. T. G. de Dávila, M. Rodríguez-Zubieta, D. Steinberg, D. Russo, A. Etchegaray, G. Podesta, Mar Varela |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pathology medicine.diagnostic_test Sialoblastoma business.industry Treatment options Magnetic resonance imaging Case Report General Medicine medicine.disease Multidisciplinary team 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Rare case Surgical biopsy medicine Ki67 index RB1-214 Radiology Ultrasonography 030223 otorhinolaryngology business |
| Zdroj: | Case Reports in Pathology Case Reports in Pathology, Vol 2021 (2021) |
| ISSN: | 2090-679X 2090-6781 |
| Popis: | We report a case of a newborn with two synchronous tumors—sialoblastoma and hepatoblastoma—diagnosed at 20 weeks of gestation by magnetic resonance imaging (MRI) and ultrasonography (US). The aim of this study was to describe the management of this case together with a review of the literature. Our patient had a large facial tumor associated with extremely high alpha-fetoprotein levels. Diagnosis of the tumors was made by surgical biopsy, showing typical features in both. Sialoblastoma is a potentially aggressive tumor. In our case, the Ki67 index in the sialoblastoma was between 20 and 30%, indicating a possibly unfavorable behavior. The infant underwent surgery and chemotherapy in different steps. Complete surgical resection with clean margins is considered to be the best treatment option for sialoblastoma. Only four similar cases were previously reported. Timely management by a multidisciplinary team is essential in these difficult cases. In our patient, outcome was good at the time of this report. |
| Databáze: | OpenAIRE |
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