Pulmonary manifestations of light chain deposition disease
Autor: | Ronald E. Gordon, James A. Strauchen, Lisa Rho, Libo Qiu, Alvin S. Teirstein |
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Rok vydání: | 2009 |
Předmět: |
Adult
Lung Diseases Male Pulmonary and Respiratory Medicine Pathology medicine.medical_specialty Biopsy Paraproteinemias Plasma cell dyscrasia LIGHT CHAIN DISEASE Immunoglobulin light chain Light chain deposition disease medicine Extracellular Humans Lung Aged 80 and over medicine.diagnostic_test business.industry Middle Aged medicine.disease medicine.anatomical_structure Monoclonal Female Immunoglobulin Light Chains business |
Zdroj: | Respirology. 14:767-770 |
ISSN: | 1440-1843 1323-7799 |
DOI: | 10.1111/j.1440-1843.2009.01560.x |
Popis: | Light chain deposition disease (LCDD) is a rare condition characterized by extracellular light chain deposition in tissues. Patients commonly have an underlying plasma cell dyscrasia, and produce excess levels of monoclonal light chains. Renal involvement is the most common clinical manifestation. Rarely, light chains are deposited in the lung. We present the pathologic and radiographic findings of three patients with biopsy-proven pulmonary light chain disease and a review of the literature. |
Databáze: | OpenAIRE |
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