B-type natriuretic peptide levels are correlated with birth-weight discordance in monochorionic-diamniotic twins without twin–twin transfusion syndrome
| Autor: | A, Moriichi, K, Cho, Y, Furuse, T, Akimoto, Y, Kaneshi, T, Yamada, M, Morikawa, H, Minakami |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Amniotic fluid medicine.drug_class Birth weight Twins Sensitivity and Specificity Umbilical cord Ventricular Function Left Young Adult Pregnancy Internal medicine Natriuretic Peptide Brain Natriuretic peptide medicine Birth Weight Humans Prospective Studies cardiovascular diseases Young adult Prospective cohort study Twin Twin Transfusion Syndrome business.industry Infant Newborn Obstetrics and Gynecology Fetofetal Transfusion medicine.disease Endocrinology medicine.anatomical_structure Pediatrics Perinatology and Child Health cardiovascular system Cardiology Female business human activities hormones hormone substitutes and hormone antagonists circulatory and respiratory physiology |
| Zdroj: | Journal of Perinatology. 33:182-187 |
| ISSN: | 1476-5543 0743-8346 |
| DOI: | 10.1038/jp.2012.94 |
| Popis: | To determine whether B-type natriuretic peptide (BNP) levels in umbilical cord blood (UCB) and amniotic fluid (AF) are correlated with birth-weight discordances in monochorionic-diamniotic twins.The UCB-BNP and AF-BNP levels were determined at birth in 36 twin-pairs without twin-twin transfusion syndrome (TTTS).Both the UCB-BNP and the AF-BNP levels were significantly higher among twins with either a birth-weight discordance ≥20% (141.6 versus 52.9 pg ml(-1) for UCB-BNP, 38.0 versus 17.2 pg ml(-1) for AF-BNP) or cardiac dysfunction at birth (167.2 versus 56.3 pg ml(-1) for UCB-BNP, 34.9 versus 19.0 pg ml(-1) for AF-BNP), compared with neonates without the respective characteristics. The UCB-BNP and AF-BNP levels in both the larger and the smaller twins were significantly correlated with birth-weight discordance.Cardiac dysfunction occurs in both larger and smaller co-twins with increasing birth-weight discordances, even in the absence of TTTS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|