Long-term Survival of Patients With Invasive Ultra-thin Cutaneous Melanoma
| Autor: | Mauro Alaibac, Elisa Zonta, Marco Rastrelli, Carlo Riccardo Rossi, Giacomo Dal Bello, Luca Giovanni Campana, Antonella Vecchiato |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Skin Neoplasms Time Factors Biopsy Observational Study Single Center Risk Assessment Disease-Free Survival Cohort Studies 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Long term survival 80 and over Needle Humans Medicine Aged Aged 80 and over Biopsy Needle Female Follow-Up Studies Immunohistochemistry Melanoma Middle Aged Neoplasm Invasiveness Neoplasm Staging Retrospective Studies Survival Analysis Medicine (all) Stage (cooking) neoplasms Survival rate Not evaluated business.industry Incidence (epidemiology) General Medicine medicine.disease Dermatology Surgery 030220 oncology & carcinogenesis Cutaneous melanoma business Research Article |
| Zdroj: | Medicine |
| ISSN: | 0025-7974 |
| DOI: | 10.1097/md.0000000000002452 |
| Popis: | The incidence of cutaneous melanoma is increasing worldwide, especially for thin melanoma (Breslow ≤1 mm). Thin cutaneous melanoma has a favorable prognosis but there are few data about the prognosis of patients with ultra-thin cutaneous melanoma (Breslow ≤ 0.5 mm). Our aim was to investigate the disease-free survival among patients with invasive cutaneous melanoma with Breslow ≤ 0.5 mm after 10 years from the initial diagnosis. A retrospective review of 240 cutaneous melanoma patients with Breslow ≤ 0.5 mm was performed. Recurrence, death from cutaneous melanoma, and disease-free survival were all identified. In the whole group of patients, we observed only 2 deaths from cutaneous melanoma. Median follow-up was 13, 11 years. Among all 240 patients, 221 were alive and disease free, 2 died of cutaneous melanoma, 11 died of other non-neoplastic diseases, 5 died of other neoplastic diseases different from melanoma, and 1 patient had a local recurrence; therefore the 10-year melanoma survival rate was 99.6%. Our data indicate that death from cutaneous melanoma in the group of patients with Breslow ≤0.5 mm was a very rare event and that diagnosis at this stage dramatically decreases the risk of developing metastatic tumors to a |
| Databáze: | OpenAIRE |
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