Association between self‐reported appetite and clinical outcomes of peritoneal dialysis patients: Findings from a low middle‐income country
| Autor: | Guttiga Halue, Brian Bieber, Kittisak Tangjittrong, David W. Johnson, Piyawan Kittiskulnam, Talerngsak Kanjanabuch, Pongpratch Puapatanakul, Kriang Tungsanga, Pichet Lorvinitnun, Chanchana Boonyakrai, Krit Pongpirul |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment media_common.quotation_subject 030232 urology & nephrology Appetite Peritonitis 030204 cardiovascular system & hematology Peritoneal dialysis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Humans Patient Reported Outcome Measures Prospective Studies Hypoalbuminemia Poverty Aged media_common Creatinine Proportional hazards model business.industry General Medicine Middle Aged Thailand medicine.disease Treatment Outcome Poor Appetite chemistry Nephrology Income Female Self Report Hemodialysis business Peritoneal Dialysis |
| Zdroj: | Nephrology. 26:454-462 |
| ISSN: | 1440-1797 1320-5358 |
| Popis: | Patient-reported outcome measures (PROM) has gained international recognition as important predictors of clinical outcomes in peritoneal dialysis (PD). We sought to understand the associations between patient-reported appetite and clinical outcomes.In the Thailand Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS), 690 of 848 randomly selected PD patients from 22 facilities reported their appetite by using the short form (three items) of the Appetite and Diet Assessment Tool (ADAT), between 2016 and 2018. In this questionnaire, the patients rated their appetite as well as a change in appetite over time. Cox proportional hazards model regression was used to estimating associations between self-reported appetite and clinical outcomes, including mortality, haemodialysis (HD) transfer and peritonitis.Half of the PD patients reported a good appetite, whereas 34% and 16% reported fair and poor appetites, respectively. Poor appetite was more prevalent among female, diabetic, congestive heart failure, older age and patients who had worse nutritional indicators, including lower time-averaged serum albumin and serum creatinine concentrations, as well as a higher proportions of hypokalaemia and severe hypoalbuminemia (serum albumin3 g/dl). After adjusting for age, sex, comorbidities, and PD vintage, poor appetite was associated with increased risks of peritonitis (adjusted hazard ratio [HR] 1.73, 95% confidence interval [CI] 1.14-2.62), HD transfer (adjusted HR 2.25, 95% CI 1.24-4.10) and all-cause mortality (adjusted HR 1.60, 95% CI 1.08-2.39) compared to patients with good appetite.Patient-reported poor appetite was independently associated with higher risks of peritonitis, HD transfer and all-cause mortality. This warrants further investigation to identify effective interventions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|