Evidence of Pre-Roman Tribal Genetic Structure in Basques from Uniparentally Inherited Markers
| Autor: | Begoña, Martínez-Cruz, Christine, Harmant, Daniel E, Platt, Wolfgang, Haak, Jeremy, Manry, Eva, Ramos-Luis, David F, Soria-Hernanz, Frédéric, Bauduer, Jasone, Salaberria, Bernard, Oyharçabal, Lluis, Quintana-Murci, David, Comas, Miguel G, Vilar |
|---|---|
| Přispěvatelé: | Conseil régional d'Aquitaine, Conseil Général des Pyrénées-Atlantiques, Conseil des Elus du Pays-Basque, Centre National de la Recherche Scientifique (France), Association Sang 64 (France), Universitat Pompeu Fabra [Barcelona] (UPF), Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), IBM T. J. Watson Research Centre, University of Adelaide, CIBER de Enfermedades Raras (CIBERER), National Geographic Society, Maladies Rares - Génétique et Métabolisme (MRGM), Université Bordeaux Segalen - Bordeaux 2-Hôpital Pellegrin-Service de Génétique Médicale du CHU de Bordeaux, Centre de recherche sur la langue et les textes basques (IKER), Université de Pau et des Pays de l'Adour (UPPA)-Université Bordeaux Montaigne (UBM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by the HIPVAL (Histoire des populations et variation linguistique dans les Pyrénées de l’Ouest) project. The HIPVAL project was made possible by grants from the 'Conseil Régional d’Aquitaine, the Conseil Général des Pyrénées-Atlantiques, the Conseil des Elus du Pays-Basque,' the Centre National de la Recherche Scientifique (CNRS) (interdisciplinary programme), OHLL (Origine de l’Homme, des Langues et du Langage), and Association Sang 64. |
| Rok vydání: | 2012 |
| Předmět: |
Genetic Markers
Population Context (language use) Biology DNA Mitochondrial White People Haplogroup Ethnicity Genetics Tribe Humans Human populations education Molecular Biology Ecology Evolution Behavior and Systematics Basques Ethnogenesis [SDV.GEN]Life Sciences [q-bio]/Genetics education.field_of_study Chromosomes Human Y Geography Y chromosome Genetic heterogeneity Mitochondrial DNA Tribal genetic structure Genealogy Genetics Population Haplotypes Genetic structure Haplogroups Gene pool |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Molecular Biology and Evolution Molecular Biology and Evolution, 2012, 29 (9), pp.2211-2222. ⟨10.1093/molbev/mss091⟩ |
| ISSN: | 1537-1719 0737-4038 |
| DOI: | 10.1093/molbev/mss091 |
| Popis: | Martínez-Cruz, Begoña et al. Basque people have received considerable attention from anthropologists, geneticists, and linguists during the last century due to the singularity of their language and to other cultural and biological characteristics. Despite the multidisciplinary efforts performed to address the questions of the origin, uniqueness, and heterogeneity of Basques, the genetic studies performed up to now have suffered from a weak study design where populations are not analyzed in an adequate geographic and population context. To address the former questions and to overcome these design limitations, we have analyzed the uniparentally inherited markers (Y chromosome and mitochondrial DNA) of ∼900 individuals from 18 populations, including those where Basque is currently spoken and populations from adjacent regions where Basque might have been spoken in historical times. Our results indicate that Basque-speaking populations fall within the genetic Western European gene pool, that they are similar to geographically surrounding non-Basque populations, and also that their genetic uniqueness is based on a lower amount of external influences compared with other Iberians and French populations. Our data suggest that the genetic heterogeneity and structure observed in the Basque region result from pre-Roman tribal structure related to geography and might be linked to the increased complexity of emerging societies during the Bronze Age. The rough overlap of the pre-Roman tribe location and the current dialect limits support the notion that the environmental diversity in the region has played a recurrent role in cultural differentiation and ethnogenesis at different time periods. © 2012 The Author(s). This work was supported by the HIPVAL (Histoire des populations et variation linguistique dans les Pyrénées de l’Ouest) project. The HIPVAL project was made possible by grants from the “Conseil Régional d’Aquitaine, the Conseil Général des Pyrénées-Atlantiques, the Conseil des Elus du Pays-Basque,” the Centre National de la Recherche Scientifique (CNRS) (interdisciplinary programme), OHLL (Origine de l’Homme, des Langues et du Langage), and Association Sang 64. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|