Impact of ACE I/D gene polymorphism on blood pressure, heart rate variability and nitric oxide responses to the aerobic exercise in hypertensive elderly
| Autor: | Paulo de Tarso Veras Farinatti, Sérgio Rodrigues Moreira, Marcelo Magalhães Sales, Herbert Gustavo Simões, Hugo A.P. Santana, Otávio de Toledo Nóbrega |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Mean arterial pressure Idosas Respuesta Cardiometabólica lcsh:Special situations and conditions lcsh:Medicine Genótipo Enzima Conversora Angiotensina 030204 cardiovascular system & hematology Exercício físico Nitric oxide Cardiometabolic responses Older women 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Physiology (medical) Internal medicine medicine Respostas cardiometabólicas Heart rate variability Aerobic exercise Orthopedics and Sports Medicine lcsh:Sports medicine biology business.industry lcsh:RC952-1245 lcsh:R ACE genotype Physical exercise Angiotensin-converting enzyme 030229 sport sciences Ancianas Ejercicio Físico Blood pressure Mean blood pressure Endocrinology chemistry biology.protein business Genotipo Enzima Conversora Angiotensina lcsh:RC1200-1245 Anaerobic exercise |
| Zdroj: | Revista Andaluza de Medicina del Deporte, Vol 11, Iss 2, Pp 57-62 (2018) Revista Andaluza de Medicina del Deporte v.11 n.2 2018 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| ISSN: | 1888-7546 |
| Popis: | Objective: To analyze the impact of I/D polymorphism of the angiotensin-converting enzyme gene on the responses of 24 h blood pressure, heart rate variability and nitric oxide after moderate aerobic exercise session. Method: Twenty seven hypertensive elderly were genotyped for the I/D polymorphism of the angiotensin-converting enzyme gene (D/D: n = 9; I/D: n = 9; I/I: n = 9) and performed a bout of aerobic exercise at 90% of anaerobic threshold. Measurements of mean blood pressure, heart rate variability and nitric oxide were performed before and during 24 h post-aerobic exercise session. Results: The D/D genotype showed impaired mean arterial pressure responses (elevation) in the nocturnal sleep (10:30 pm to 06:30 am) post-aerobic exercise when compared to rest (D/D= −4.2 ± 8.1 mmHg; p > 0.05, I/D = −9.2 ± 9.1 mmHg; p 0.05), showed reduced elevation of nitric oxide between genotypes immediately after aerobic exercise (D/D = 12.8 ± 135.3 μM and I/D = −8.7 ± 69.0 μM vs. I/I = 132.9 ± 188.7 μM; p 0.05, I/D = –9.2 ± 9.1 mmHg; p 0.05, I/D = –9.2 ± 9.1 mmHg; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|