'Bull’s eye' appearance of hepatocellular adenomas in patients with glycogen storage disease type I — atypical magnetic resonance imaging findings: Two case reports
Autor: | Daniele Marin, Federica Vernuccio, Stephanie Austin, Priya S. Kishnani, Mathias Meyer, Cynthia D. Guy |
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Rok vydání: | 2021 |
Předmět: |
Pathology
medicine.medical_specialty Gadoxetate Disodium 03 medical and health sciences Magnetic resonance imaging 0302 clinical medicine Case report medicine Glycogen storage disease In patient Glycogen storage disease type I medicine.diagnostic_test business.industry General Medicine Hepatocellular adenoma equipment and supplies medicine.disease digestive system diseases Bull’s eye 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Gadoxetate disodium Bull's Eye business human activities |
Zdroj: | World Journal of Clinical Cases |
ISSN: | 2307-8960 |
Popis: | BACKGROUND Hepatocellular adenomas are rare tumors that can occur in patients with glycogen storage disease type I. CASE SUMMARY We herein report two cases of histologically proven hepatocellular adenomas in patients with glycogen storage disease type I. Magnetic resonance imaging (MRI) was performed after bolus injection of gadoxetate disodium, a liver-specific gadolinium-based MRI contrast agent. In the present cases, some of the hepatocellular adenomas showed unexpectedly a “bull’s eye” appearance on T2-weighted and post-contrast images, which was not previously described as imaging findings of hepatocellular adenomas in glycogen storage disease. A bull’s eye appearance on T2-weighted images can be encountered in both benign (i.e., abscess) or malignant (i.e., epithelioid hemangioendothelioma, cholangio-carcinoma, and metastases) hepatic lesions. CONCLUSION We present two cases of hepatocellular adenomas in patients with glycogen storage disease type 1, in which gadoxetate disodium-MRI showed atypical imaging findings for hepatocellular adenomas. At present there is no systematic study evaluating MRI findings of hepatocellular adenomas in patients with glycogen storage disease, further studies are needed to specifically investigate this issue. |
Databáze: | OpenAIRE |
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