Physostigmine and norepinephrine: Effects of injection into the amygdala on taste associations
| Autor: | Maureen E. Ellis, Raymond P. Kesner |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Male
Taste Physostigmine Experimental and Cognitive Psychology Amygdala Norepinephrine (medication) Norepinephrine Behavioral Neuroscience Avoidance Learning medicine Animals Humans Neophobia medicine.disease Rats Apomorphine medicine.anatomical_structure Phobic Disorders Taste aversion Psychology Neuroscience Acetylcholine medicine.drug |
| Zdroj: | Physiology & Behavior. 27:203-209 |
| ISSN: | 0031-9384 |
| DOI: | 10.1016/0031-9384(81)90258-4 |
| Popis: | The present investigation was conducted to determine whether norepinephrine or acetylcholine systems of the amygdala could be involved in two adaptive feeding behaviors in the rat: development of taste aversion and recovery from neophobia. In a taste aversion paradigm, a single bilateral injection of physostigmine directly into the amygdala at the onset of an apomorphine-induced illness experience produced a time-dependent attenuation in the development of taste aversion; in contrast, norepinephrine had no disruptive effects. In a neophobia paradigm, norepinephrine injected directly into the amygdala after a novel taste experience resulted in a time-dependent attenuation in recovery from neophobia; however, physostigmine produced no disruptive effects. Hence, acetylcholine appears to mediate taste-illness associations, while norepinephrine plays an important role in recovery from neophobia, i.e., taste-“learned safety” associations. |
| Databáze: | OpenAIRE |
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