Radiation dose of CT coronary angiography in clinical practice: Objective evaluation of strategies for dose optimization
| Autor: | Satvir Atwal, DP Lipkin, Avijit Lahiri, Ajay Yerramasu, Shreenidhi Venuraju, Dennis A. Goodman |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Coronary angiography medicine.medical_specialty Image quality Cardiac-Gated Imaging Techniques Contrast Media Coronary Artery Disease Signal-To-Noise Ratio Coronary Angiography Radiation Dosage Statistics Nonparametric Coronary artery disease Bayesian multivariate linear regression Humans Medicine Radiology Nuclear Medicine and imaging Prospective Studies Prospective gating business.industry Radiation dose General Medicine Middle Aged medicine.disease Clinical Practice Coronary arteries Cross-Sectional Studies medicine.anatomical_structure Linear Models Female Radiology Tomography X-Ray Computed business Nuclear medicine Algorithms |
| Zdroj: | European Journal of Radiology. 81:1555-1561 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2011.02.040 |
| Popis: | Background CT coronary angiography (CTCA) is an evolving modality for the diagnosis of coronary artery disease. Radiation burden associated with CTCA has been a major concern in the wider application of this technique. It is important to reduce the radiation dose without compromising the image quality. Objectives To estimate the radiation dose of CTCA in clinical practice and evaluate the effect of dose-saving algorithms on radiation dose and image quality. Methods Effective radiation dose was measured from the dose-length product in 616 consecutive patients (mean age 58 ± 12 years; 70% males) who underwent clinically indicated CTCA at our institution over 1 year. Image quality was assessed subjectively using a 4-point scale and objectively by measuring the signal- and contrast-to-noise ratios in the coronary arteries. Multivariate linear regression analysis was used to identify factors independently associated with radiation dose. Results Mean effective radiation dose of CTCA was 6.6 ± 3.3 mSv. Radiation dose was significantly reduced by dose saving algorithms such as 100 kV imaging (−47%; 95% CI, −44% to −50%), prospective gating (−35%; 95% CI, −29% to −40%) and ECG controlled tube current modulation (−23%; 95% CI, −9% to −34%). None of the dose saving algorithms were associated with a significant reduction in mean image quality or the frequency of diagnostic scans ( P = non-significant for all comparisons). Conclusion Careful application of radiation-dose saving algorithms in appropriately selected patients can reduce the radiation burden of CTCA significantly, without compromising the image quality. |
| Databáze: | OpenAIRE |
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