Factors associated with bacteremia in young infants with urinary tract infection
| Autor: | Ran Nir-Paz, Dan Engelhard, Benjamin Z. Koplewitz, Polina Stepensky, Ariel Tenenbaum, Diana Averbuch, Rebecca Brooks, Ari Simckes |
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| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Male Pediatrics medicine.medical_specialty Urinary system MEDLINE Bacteremia urologic and male genital diseases Young infants medicine Humans Israel Retrospective Studies business.industry Infant Newborn Infant Retrospective cohort study bacterial infections and mycoses medicine.disease female genital diseases and pregnancy complications Infectious Diseases Jews Pediatrics Perinatology and Child Health Urinary Tract Infections Female business |
| Zdroj: | The Pediatric infectious disease journal. 33(6) |
| ISSN: | 1532-0987 |
| Popis: | Urinary tract infection (UTI) is the most frequent severe bacterial infection in infants. Up to 31% of infants with UTI have bacteremia.We retrospectively identified all infants aged 0-2 months who were managed in our hospital with UTI during a 1-year period. Those with bacteremia were compared with those without bacteremia, according to the following variables: ethnicity, age, gender, white blood cell and polymorphonuclear counts, C-reactive protein, urinalysis and blood creatinine values as related to age-appropriate norms, imaging and outcome.We identified 81 infants with 82 episodes of UTI. Most occurred in males (72.8%) and 35 (42.7%) were in infants of non-Jewish origin. In 14/81 (17.3%) of episodes, Escherichia coli was cultured from blood. In multivariate analysis, increased blood creatinine levels (P = 0.004) and non-Jewish origin (P = 0.006) were associated with bacteremia. Time to defervescence was significantly longer in bacteremic versus nonbacteremic children (P = 0.018). Duration of hospitalization was longer in bacteremic infants-10 (7-17) days in bacteremic versus 7 (1-14) days in nonbacteremic children (P0.001).In infants aged 0-2 months with UTI, increased blood creatinine value at admission was associated with bacteremia. This value provides an additional clue on admission, independent of personal judgment, to help identify infants at higher risk for bacteremia, prolonged hospitalization and possible complications. |
| Databáze: | OpenAIRE |
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