Autor: |
Frederik Jan Rita Rombouts, Nicolas Fleury-Brégeot, Daniel Oehlrich, Floriane Beaumard, Marc Presset, Gary A. Molander, Virginie Colombel |
Rok vydání: |
2012 |
Předmět: |
|
Zdroj: |
The Journal of organic chemistry. 77(22) |
ISSN: |
1520-6904 |
Popis: |
The introduction of an alkoxyethyl moiety onto aromatic substructures has remained a long-standing challenge for synthetic organic chemists. The main reasons are the inherent instability of alkoxyethylmetallic species and the lack of general procedures to access them. A new method utilizing a cross-coupling strategy based on the exceptional properties of organotrifluoroborates has been developed, and the method allows an easy and efficient installation of this unit on a broad range of aryl and heteroaryl bromides. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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