Surgical and functional outcomes and survival following Colon Cancer surgery in the aged: a study protocol for a prospective, observational multicentre study

Autor: Marja Hyöty, Susanna Niemeläinen, Anu Ehrlich, Jyrki Kössi, Heini Huhtala, Esa Jämsen
Přispěvatelé: Tampere University, Department of Gastroenterology, Clinical Medicine, Health Sciences, Department of Geriatrics, HUS Helsinki and Uusimaa Hospital District, Clinicum, HYKS erva, Päijät-Häme Welfare Consortium
Rok vydání: 2021
Předmět:
Male
Cancer Research
Colorectal cancer
COLORECTAL-CANCER
Study Protocol
0302 clinical medicine
Quality of life
Surgical oncology
POSTOPERATIVE OUTCOMES
Health care
030212 general & internal medicine
Functional ability
Prospective Studies
POPULATION
RC254-282
Aged patients
Aged
80 and over
education.field_of_study
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
3. Good health
Colon cancer
Oncology
030220 oncology & carcinogenesis
Colonic Neoplasms
Female
medicine.medical_specialty
3122 Cancers
Population
3121 Internal medicine
VALIDATION
GERIATRIC ASSESSMENT
03 medical and health sciences
Genetics
medicine
Humans
short-term outcome
education
FRAILTY
Protocol (science)
Functional ability
short-term outcome
OLDER PATIENTS
business.industry
MORTALITY
3126 Surgery
anesthesiology
intensive care
radiology
medicine.disease
Survival Analysis
Surgery
3141 Health care science
HEALTH-CARE
Observational study
CONSENSUS
business
Zdroj: BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
ISSN: 1471-2407
0390-4121
Popis: Background The number of colorectal cancer patients increases with age. The decision to go through major surgery can be challenging for the aged patient and the surgeon because of the heterogeneity within the older population. Differences in preoperative physical and cognitive status can affect postoperative outcomes and functional recovery, and impact on patients’ quality of life. Methods / design A prospective, observational, multicentre study including nine hospitals to analyse the impact of colon cancer surgery on functional ability, short-term outcomes (complications and mortality), and their predictors in patients aged ≥80 years. The catchment area of the study hospitals is 3.88 million people, representing 70% of the population of Finland. The data will be gathered from patient baseline characteristics, surgical interventional data, and pre- and postoperative patient-questionnaires, to an electronic database (REDCap) especially dedicated to the study. Discussion This multicentre study provides information about colon cancer surgery’s operative and functional outcomes on older patients. A further aim is to find prognostic factors which could help to predict adverse outcomes of surgery. Trial registration ClinicalTrials.gov (NCT03904121). Registered on 1 April 2019.
Databáze: OpenAIRE
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