Triton X-100 catalyzed synthesis of α-aminophosphonates

Autor:	Cirandur Suresh Reddy, Nemallapudi Bakthavatchala Reddy, Sandip K. Nayak, Chinthaparthi Radha Rani, Kunda Uma Maheswara Rao, Chereddy Syama Sundar
Rok vydání:	2016
Předmět:	Antifungal Chemistry(all) medicine.drug_class General Chemical Engineering 010402 general chemistry 01 natural sciences Aldehyde Catalysis lcsh:Chemistry chemistry.chemical_compound Pulmonary surfactant medicine Organic chemistry α-Aminophosphonates GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) ComputingMilieux_MISCELLANEOUS chemistry.chemical_classification Reaction conditions Non-ionic surfactant catalyst Triton X-100 010405 organic chemistry Dialkylphosphites Condensation General Chemistry 0104 chemical sciences lcsh:QD1-999 chemistry Yield (chemistry) Chemical Engineering(all)
Zdroj:	Arabian Journal of Chemistry, Vol 9, Iss S1, Pp S685-S690 (2016)
ISSN:	1878-5352
DOI:	10.1016/j.arabjc.2011.07.025
Popis:	Synthesis of α-aminophosphonates by a three-component condensation of an aldehyde, amines and dialkyl phosphites in the presence of a non-ionic surfactant Triton X-100 catalyst at 70 °C in aqueous medium is accomplished. The advantages are high yield, mild reaction conditions, simple work-up and eco-friendliness. All the newly-synthesized compounds (4a–j) exhibited moderate in vitro antibacterial and antifungal activities.
Databáze:	OpenAIRE
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