Smoking history, nicotine dependence and opioid use in patients with chronic non-malignant pain
| Autor: | Hanne Irene Jensen, Karin Bruun Plesner, J Højsted |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study media_common.quotation_subject Denmark Population Nicotine 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Internal medicine Surveys and Questionnaires medicine Prevalence Humans In patient Psychiatry education media_common Aged Aged 80 and over education.field_of_study business.industry Addiction Smoking Chronic pain Opioid-Related Disorders General Medicine Tobacco Use Disorder Middle Aged medicine.disease Former Smoker Analgesics Opioid Anesthesiology and Pain Medicine Cross-Sectional Studies Female Chronic Pain business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Plesner, K, Jensen, H I & Højsted, J 2016, ' Smoking history, nicotine dependence and opioid use in patients with chronic non-malignant pain ', Acta Anaesthesiologica Scandinavica, vol. 60, no. 7, pp. 988-994 . https://doi.org/10.1111/aas.12741 |
| ISSN: | 1399-6576 |
| DOI: | 10.1111/aas.12741 |
| Popis: | Background Previous studies have demonstrated a positive association between smoking and addiction to opioids in patients with chronic non-malignant pain. This could be explained by a susceptibility in some patients to develop addiction. Another explanation could be that nicotine influences both pain and the opioid system. The objective of the study was to investigate whether smoking, former smoking ± nicotine use and nicotine dependence in patients with chronic non-malignant pain were associated with opioid use and addiction to opioids. Methods The study was a cross-sectional study carried out at a multidisciplinary Danish pain centre. All patients aged 18 or more in treatment at the pain centre on the 1st of September 2013 were invited to participate in the study. Results A total of 98 patients (65%) participated in the study. The prevalence of current smokers was twice as high as in the general population. The prevalence of patients using opioids was 54% and the prevalence of addiction to opioids was 6%. No significant differences in addiction were found between the different smoking groups, but smokers and former smokers using nicotine tended to use opioids more frequently and at higher doses than never smokers and former smokers not using nicotine. Conclusions The study supports previous evidence that smoking is associated with chronic pain. Our data suggest that information about use of nicotine substitution in chronic non-malignant patients are relevant both in a clinical setting, but also in future studies of the association between smoking habits, pain and opioid use. |
| Databáze: | OpenAIRE |
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