Effect of aerobic training on hot flushes and quality of life—a randomized controlled trial

Autor: Clas-Håkan Nygård, Eija Tomás, Jaana M Moilanen, Katriina Ojala, Reetta Heinonen, Tomi S. Mikkola, Kirsi Mansikkamäki, Riitta Luoto, Jani Raitanen
Rok vydání: 2012
Předmět:
Zdroj: Annals of Medicine
ISSN: 1365-2060
0785-3890
DOI: 10.3109/07853890.2011.583674
Popis: Background and objective. To estimate whether aerobic training has an effect on frequency of hot flushes or quality of life. Design. A randomized controlled trial. Participants and setting. Symptomatic, sedentary women (n = 176), 43–63 years, no current use of hormone therapy. Intervention. Unsupervised aerobic training for 50 minutes four times per week during 6 months. Outcomes. Hot flushes as measured with Women's Health Questionnaire (WHQ) and Health-Related Quality of Life (HRQoL, SF-36), daily reported hot flushes on phone-based diary, cardiorespiratory fitness (CRF), and body composition. Results. Intervention group had larger decrease in the frequency of night-time hot flushes based on phone diary (P for month X group = 0.012), but not on WHQ scale. Intervention group had less depressed mood (P= 0.01) than control women according to change in WHQ score. Changes in WHQ score in depressed mood (P = 0.03) and menstrual symptoms (P=0.01) in the intervention group were significantly dependent on frequency of training sessions. HRQoL was improved among the intervention group women in physical functioning (P= 0.049) and physical role limitation (P= 0.017). CRF improved (P= 0.008), and lean muscle mass increased (P= 0.046) significantly in the intervention group as compared to controls. Conclusions. Aerobic training may decrease the frequency of hot flushes and improve quality of life among slightly overweight women.
Databáze: OpenAIRE