Evaluation of right side foetal myocardial performance index in pregestational and gestational diabetes mellitus
| Autor: | Nura Fitnat Tobaş Selçuki, Didem Esin, Uğur Turhan, Mehmet Aytaç Yüksel, Gökalp Şenol, Berna Aslan Çetin, Zafer Bütün, Ahmet Tayyar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Pregnancy in Diabetics Foetal heart Ultrasonography Prenatal 03 medical and health sciences 0302 clinical medicine Fetal Heart Pregnancy Internal medicine medicine Humans Prospective Studies Myocardial Performance Index 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Stroke Volume Gestational Diabetesmellitus medicine.disease Myocardial Contraction Echocardiography Doppler Gestational diabetes Diabetes Gestational Cross-Sectional Studies Right Heart 030220 oncology & carcinogenesis Case-Control Studies Right heart Cardiology Female business Myocardial Performanceindex |
| Popis: | The aim of our study is to investigate the myocardial performance index (MPI) of the right side of the foetal heart in pregestational and gestational diabetes mellitus and to compare it with non-diabetic pregnancies. This prospective cross-sectional study was conducted between August 2018 and March 2019 at Kanuni Sultan Suleyman Research and Training Hospital. Women with pregestational or gestational diabetes mellitus at 24-34 weeks of gestation were included in the study and non-diabetic pregnant women were included as the control group. MPI of the right side of the foetal heart were evaluated and compared between the groups. A total of 65 pregestational or gestational diabetic patients and 65 non-diabetic patients were included in the study. Isovolumetric contraction time and isovolumetric relaxation time values were significantly longer in the diabetic group (p < .001). Ejection time values were significantly shorter in the diabetic group (p < .001). MPI values were significantly higher in the diabetic group than the non-diabetic group (p < .001). In conclusion, MPI of the right side of the foetal heart is significantly higher in pregestational and gestational diabetes than in the non-diabetic group.IMPACT STATEMENT What is already known on this subject? Gestational diabetes mellitus causes foetal cardiomyopathy and foetal diastolic dysfunction. Myocardial performance index (MPI) is a non-invasive, Doppler-derived myocardial performance assessment that is independent of both heart rate and ventricular anatomy. What do the results of this study add? MPI of the right side of the foetal heart was significantly higher in pregestational and gestational diabetes than in the non-diabetic group. There was no difference in right ventricular MPI between pregestational and gestational groups in diabetic pregnancies, and between insulin using and not insulin using groups. What are the implications of these findings for clinical practice and/or further research? Our study results are promising. MPI of the right side of the foetal heart is significantly higher in pregestational and gestational diabetes than in the non-diabetic group. Prospective cohort studies evaluating serial MPI and evaluating by postpartum foetal echocardiography are needed to evaluate possible adverse effects of diabetes on foetal cardiac functions. |
| Databáze: | OpenAIRE |
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