Cancer Nanotechnology: Recent Trends and Developments in Strategies for Targeting Cancer Cells to Improve Cancer Imaging and Treatment
| Autor: | Yifei Li, Xiaoling Zhou, Jingyao Xu, Yudan Tian |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Treatment response medicine.medical_specialty Clinical Biochemistry Early detection Antineoplastic Agents Nanotechnology 02 engineering and technology Cancer imaging Cancer nanotechnology Imaging modalities 03 medical and health sciences Drug Delivery Systems Neoplasms medicine Animals Humans Malignant cells Medical physics Pharmacology Cancer 021001 nanoscience & nanotechnology medicine.disease Nanostructures 030104 developmental biology Cancer cell 0210 nano-technology |
| Zdroj: | Current Drug Metabolism. 18:266-279 |
| ISSN: | 1389-2002 |
| DOI: | 10.2174/1389200218666170116113103 |
| Popis: | OBJECTIVE Nanotechnology is a multidisciplinary field, which have the potential to cover applications in many subjects such as biology, chemistry and physics. METHOD The combined efforts of these subjects can lead to the successful engineering of nanodevices and nanovectors for targeted delivery and sensing/detection of cancer cells/tissues. The modulation of nanomaterials at surface and bulk level further adds value to this technology and develop strategies for early detection of precancerous and malignant cells from biological fluids. Furthermore, the novel nanotechnology-based imaging modalities have the prospects to offer non-invasive cancer imaging and treatment response study in real-time. RESULT This review covers the advantages of nanotechnology, which have been exploited for effective and targeted delivery of anti-cancer agents. CONCLUSION Moreover, the initiatives taken by National Cancer Laboratory, USA to improve the clinical success of nanomedicines and nanovectors have also been comprehensively summarized. |
| Databáze: | OpenAIRE |
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