Choroidal Lymphoma: Diagnostic Value of Combined Indocyanine Green Angiography and Optical Coherence Tomography

Autor: Marco Pellegrini, Chiara Preziosa, Antonio Yaghy, Megan Ruben, Alessandro Invernizzi, Adrian T. Fung, Giovanni Staurenghi, Carol L. Shields
Rok vydání: 2022
Předmět:
Zdroj: Ocular Immunology and Inflammation. 31:263-270
ISSN: 1744-5078
0927-3948
DOI: 10.1080/09273948.2022.2026407
Popis: To compare multimodal imaging findings in patients with choroidal lymphoma (CL).Multicenter retrospective observational case series. Multimodal imaging features of patients with CL were reviewed with particular attention to the patterns of choroidal infiltration on indocyanine green angiography (ICGA) and optical coherence tomography (OCT).Eighteen eyes of 15 patients were included in this study. Average tumor thickness on ultrasonography was 2.6 mm (range, 1.2-5.7 mm). Choroidal infiltration on ICGA was characterized by multifocal, round areas (300-500 microns diameter) of hypocyanescence in all cases, whereas OCT at the same region disclosed diffuse choroidal infiltration. By OCT, the tumor surface contour was primarily placid (22%), dome-shaped (11%), or undulating (67%).In this analysis of eyes with CL, ICGA demonstrated multifocal sub-millimeter regions of choroidal hypocyanescence whereas OCT documented diffuse choroidal infiltration. This incongruence could be a distinctive diagnostic feature of choroidal lymphoma, assisting with differentiation from other pathological entities.
Databáze: OpenAIRE