Supplemental Figures S1-S5, Table S1 from Development of siRNA Payloads to Target KRAS-Mutant Cancer

Autor: Scott W. Lowe, Frank McCormick, Ji Luo, Johannes Zuber, Joseph O. Carver, Danielle Grace, Dennis J. Hsu, Liam C. Lee, Vishal Thapar, Cayde D. Ritchie, Chih-Shia Lee, Christof Fellmann, Tina L. Yuan
Rok vydání: 2023
Popis: Supplemental Figure S1. Sensor-based generation of a functionally validated sh/siRNA library targeting Ras pathway genes. Figure S2. Validation of Sensor siRNAs targeting components in the MAPK pathway. Figure S3. Dose dependent off-target effects of sh/siRNAs. Figure S4. Sensor siRNA pooling effects. Figure S5. In vivo fluorescence reporter system. Table S1. Correlation of library reads and Sensor score.
Databáze: OpenAIRE