Possible association between scleritis and lymphoma
Autor: | James T. Rosenbaum, Lyndell L Lim, Eric B. Suhler, Lynnelle K. Smith, Dongseok Choi, George A. Cioffi |
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Rok vydání: | 2007 |
Předmět: |
Adult
medicine.medical_specialty Databases Factual Disease Malignancy Cellular and Molecular Neuroscience immune system diseases hemic and lymphatic diseases medicine Humans Letters business.industry Remission Induction Middle Aged medicine.disease Institutional review board Hodgkin Disease Dermatology Sensory Systems Work-up Lymphoma Surgery Ophthalmology Increased risk Female business Uveitis Scleritis |
Zdroj: | British Journal of Ophthalmology. 91:1728-1729 |
ISSN: | 0007-1161 |
DOI: | 10.1136/bjo.2007.116830 |
Popis: | Scleritis and uveitis are ocular inflammatory diseases often presumed to be autoimmune and associated with underlying systemic disease.1 Other autoimmune diseases have been shown to confer increased risk for malignancy, including lymphoma.2–4 We present two patients diagnosed with scleritis and lymphoma and examine whether there is an association between ocular inflammatory disease and malignancy. We reviewed the records of 133 scleritis patients presenting to our ocular inflammatory diseases clinic at Oregon Health & Science University (OHSU) between 1993 and 2006. Access to this database was reviewed and approved by the OHSU institutional review board. Two patients with a diagnosis of lymphoma were identified. Patient A developed scleritis 13 years before being diagnosed with lymphoma at the age of 48. Hodgkin’s lymphoma was found incidentally on a chest x ray during repeated work up for ocular disease. Patient B was diagnosed and treated for Hodgkin’s lymphoma at the age of 24 without recurrence. She developed … |
Databáze: | OpenAIRE |
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