Vermixocins A and B, two novel metabolites from Penicillium vermiculatum

Autor:	Dušan Uhrín, Adamcová J, J. Fuska, Bohumil Proksa
Rok vydání:	1992
Předmět:	Pharmacology Antibiotics Antineoplastic biology Leukemia P388 Stereochemistry Penicillium Biological activity Fungi imperfecti biology.organism_classification Mice Heterocyclic Compounds Drug Discovery Animals P388 leukemia Heterocyclic Compounds 3-Ring Mycelium
Zdroj:	The Journal of Antibiotics. 45:1268-1272
ISSN:	1881-1469 0021-8820
Popis:	Vermixocins A and B, 3-(1'-hydroxy-3'-methylbutyl)- and 3-(1'-acetoxy-3'-methylbutyl)-11-hydroxy-4-methoxy-9-methyl-5H,7H- dibenzo[c,f][1,5]dioxocin-5-one, respectively, were isolated from the mycelium of Penicillium vermiculatum. Both metabolites showed cytotoxic effects on lympholeukemia cells P388.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b4107f3ad6d25051ce008de978c2e https://doi.org/10.7164/antibiotics.45.1268 Zobrazit plný text záznamu