Subcutaneous hyalohyphomycosis caused byFusariumin a kidney transplant recipient
| Autor: | Gwendolyn Fernandes, NK Hase, Sunil Y. Jawale, Shashir Wanjare, Vaibhav Keskar, Rupali S. Suryawanshi, Tukaram Jamale, Dinesh Mahajan |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Hyalohyphomycosis Fusarium Pathology medicine.medical_specialty medicine.medical_treatment Congenital cytomegalovirus infection Disease Critical Care and Intensive Care Medicine Postoperative Complications medicine Humans Kidney transplantation Voriconazole biology business.industry Immunosuppression General Medicine medicine.disease biology.organism_classification Kidney Transplantation Transplantation Fusariosis Nephrology Immunology Female business medicine.drug |
| Zdroj: | Renal Failure. 36:1129-1132 |
| ISSN: | 1525-6049 0886-022X |
| DOI: | 10.3109/0886022x.2014.926756 |
| Popis: | Fusarium is a filamentous opportunistic pathogenic fungus responsible for superficial as well as invasive infection in immunocompromized hosts. Net state of immunosuppression and cytomegalovirus (CMV) infection appear to predispose to this disease which is life-threatening when disseminated. Though infections with Fusarium have been widely described in hematological malignancies and hematopoietic stem cell transplant cases, they have been reported to be rare in solid organ transplant recipients, are often localized and carry a favorable prognosis. We here describe a rare case of subcutaneous non-invasive infection with Fusarium in a renal allograft recipient two and half years after transplantation. Patient had a previous history of CMV infection along with multiple other recurrent co-infections. Diagnosis was based on culture of tissue specimens yielding Fusarium species. The infection had a protracted course with persistence of lesions after treatment with voriconazole alone, requiring a combination of complete surgical excision and therapy with the anti-fungal drug. |
| Databáze: | OpenAIRE |
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