Allium cepa used as a dosimetry system in nuclear and radiological emergencies
| Autor: | M. N. Xavier, Susana O. Souza, R. Scher, S. M. Pantaleão, Riccardo Ciolini, Francesco D'Errico |
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| Rok vydání: | 2021 |
| Předmět: |
biology
DNA damage business.industry food and beverages General Physics and Astronomy 010501 environmental sciences Pharmacology biology.organism_classification medicine.disease_cause 01 natural sciences 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Radiological weapon Micronucleus test medicine Allium Dosimetry Support system Radiation protection business Genotoxicity 0105 earth and related environmental sciences |
| Zdroj: | The European Physical Journal Plus. 136 |
| ISSN: | 2190-5444 |
| Popis: | Effective provisions of preparedness and response are necessary to protect human life, health, property, and the environment in any nuclear and radiological emergency. Recently, the International Commission on Radiological Protection recognized the need to provide more quantitative guidance on environmental radiation protection to integrate these analyses. A required assessment is a correlation between dose and its effects in non-human biota. Plants are highly sensitive environmental monitors for the assessment of potentially genotoxic agents and avoid the controversial use of animal models. The Allium test is commonly used to assess genotoxicity for a wide variety of chemical and physical factors, as it allows for estimates of possible DNA damage in eukaryotes in general, including humans. In this work, onion (Allium cepa) seedlings were exposed to 20–200 mGy of $$\alpha$$ -radiation. We studied the possibility of using cytogenetic analyses of irradiated onion cells to determine the biological dose. It was observed that the increase in the frequencies of chromosomal aberrations, mitotic abnormalities, and micronuclei occurred proportional to the radiation dose, but a reduction in cytological damage was observed from 100 mGy, suggesting the onset of cytotoxic activity. Our research shows the potential of Allium cepa as a sensitive support system for dosimetry, detection, and screening of cellular effects produced by low doses of environmental radiation. |
| Databáze: | OpenAIRE |
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