1 alpha-Hydroxycholecalciferol adsorption to peritoneal dialysis bags: influence of time, glucose concentration, temperature, and albumin
| Autor: | H. Lehmann, C. Cintin, S. D. Ladefoged, Preben Joffe |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Time Factors
medicine.medical_treatment 1α hydroxycholecalciferol In Vitro Techniques Peritoneal dialysis Adsorption Albumins Dialysis Solutions medicine Humans Chronic Kidney Disease-Mineral and Bone Disorder Transplantation Chromatography Dialysis fluid business.industry Hydroxycholecalciferols Albumin Temperature Vitamina d Glucose Biochemistry Nephrology Dialisis peritoneal Dialysis (biochemistry) business Peritoneal Dialysis |
| Zdroj: | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 7(12) |
| ISSN: | 0931-0509 |
| Popis: | The present study examines the adsorptive phenomenon of 1 alpha-hydroxycholecalciferol (1 alpha-OHD3) to peritoneal dialysis bags. One minute after injection of 1 alpha-OHD3 into the dialysis bags, a significant adsorption to the bags was observed in experiments where albumin was not added. A higher temperature (37 degrees versus 23 degrees C) in bags containing 13.6 mg glucose/ml resulted in less adsorption (P < 0.05). Adding albumin to bags at 37 degrees C with a glucose concentration of 13.6 mg/ml, reduced the adsorptive phenomenon significantly (P < 0.01). Bags tested at 37 degrees C with a glucose concentration of 38.6 mg/ml resulted in a significantly higher 1 alpha-OHD3 adsorption than bags containing 13.6 mg glucose/ml (P < 0.01). It is concluded that adsorption of 1 alpha-OHD3 to dialysis bags is affected by time, albumin, temperature and glucose concentrations. Substantial amounts of 1 alpha-OHD3 is retained by the peritoneal dialysis system when albumin is not added. |
| Databáze: | OpenAIRE |
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