Plasma-Polyplumbagin-Modified Microfiber Probes: A Functional Material Approach to Monitoring Vascular Access Line Contamination
| Autor: | Marco F. Cardosi, Maria Teresa Molina, Christopher Philip Leach, James Davis |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Materials science business.product_category Bacteria Endovascular Procedures Atmospheric-pressure plasma Nanotechnology Substrate (printing) Polymer Signal Redox Carbon Micrometre chemistry Carbon Fiber Microfiber Blood Vessels Humans General Materials Science business Oxidation-Reduction Layer (electronics) |
| Zdroj: | ACS Applied Materials & Interfaces. 5:9367-9371 |
| ISSN: | 1944-8252 1944-8244 |
| DOI: | 10.1021/am402821c |
| Popis: | Atmospheric plasma treated carbon fiber filaments (10 micrometer) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood. The authors thanks the Royal Society (London, JP100125)), Ministry of Science and Innovation (SAF-2009-10399), and the Engineering and Physical Sciences Research Council (EPSRC, U.K.) for supporting this work |
| Databáze: | OpenAIRE |
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