Detection of Human Parechovirus a in Respiratory, Gastrointestinal, and Neurological Clinical Samples of Pediatric Patients from Panama

Autor: Lizette Carmen Gutierrez, Viridiana Saenz, Danilo Franco, Marlene Castillo, Brechla Moreno, Ediner Fuentes, Zeuz Capitan-Barrios, Sandra López-Vergès, Juan Miguel Pascale, Nestor Sosa, Leyda Ábrego
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: Human Parechoviruses, officially known as Parechovirus A (PeV-A), is associated with mild gastrointestinal and respiratory illness in young children, however, they may also give rise to Central Nervous System (CNS) infections and neonatal sepsis. While studies have delved into the detection of PeV-A in different populations, the detection of PeV-A in Hispanic populations in Latin American countries is not well-known. The aim of this study was to determine the presence of PeV-A in respiratory, gastrointestinal, and neurological clinical samples of pediatric patients in Panama. Two hundred samples of pediatric patients with a negative diagnosis for the main respiratory viruses, rotavirus and neurological viruses such as herpesvirus, enterovirus and cytomegalovirus, collected between 2014 and 2015, were analyzed by real-time RT-PCR. Eight positive PeV-A infections were detected, 2 in respiratory samples, 5 in stool samples and one detected in cerebrospinal fluid. This is the fisrt report of PeV-A in Panamá.
Databáze: OpenAIRE