Fu Brick Tea Manages HFD/STZ-Induced Type 2 Diabetes by Regulating the Gut Microbiota and Activating the IRS1/PI3K/Akt Signaling Pathway
| Autor: | Bangran Qi, Daoyuan Ren, Ting Li, Pengfei Niu, Xiangnan Zhang, Xingbin Yang, Jianbo Xiao |
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| Rok vydání: | 2022 |
| Předmět: |
Mice
Phosphatidylinositol 3-Kinases Diabetes Mellitus Type 2 Tea Insulin Receptor Substrate Proteins Animals Hypoglycemic Agents General Chemistry General Agricultural and Biological Sciences Proto-Oncogene Proteins c-akt Diabetes Mellitus Experimental Gastrointestinal Microbiome Signal Transduction |
| Zdroj: | Journal of agricultural and food chemistry. 70(27) |
| ISSN: | 1520-5118 |
| Popis: | The antidiabetic effects of Fu brick tea aqueous extract (FTE) and its underlying molecular mechanism in type 2 diabetes mellitus (T2DM) mice were investigated. FTE treatment significantly relieved dyslipidemia, insulin resistance (IR), and hepatic oxidative stress caused by T2DM. FTE also ameliorated the T2DM-induced gut dysbiosis by decreasing the |
| Databáze: | OpenAIRE |
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