Bone scintigraphy using Tc‐99m DPD and F18‐FDG in a patient with SAPHO syndrome
| Autor: | Konstantinos Sfetsos, Robert Pichler, W. Maschek, Klaus Weiglein, Bernhard Schmekal |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
SAPHO syndrome Hyperostosis Bone disease Immunology Bone Neoplasms Bone and Bones Diagnosis Differential Rheumatology Fluorodeoxyglucose F18 Synovitis Animals Humans Immunology and Allergy Medicine Diphosphonates medicine.diagnostic_test business.industry Osteomyelitis Acquired Hyperostosis Syndrome Organotechnetium Compounds General Medicine Middle Aged medicine.disease Pustulosis Bone scintigraphy Radiopharmaceuticals Osteitis medicine.symptom business Nuclear medicine Tomography Emission-Computed |
| Zdroj: | Scandinavian Journal of Rheumatology. 32:58-60 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.1080/03009740310000436 |
| Popis: | Synovitis (inflammatory arthritis), acne (pustulosa), palmoplantar pustulosis, hyperostosis and osteitis (bland osteomyelitis) are symptoms forming the acronym SAPHO. We present the case of a 48-year old man with sterno-costo-clavicular hyperostosis and typical pustulosis palmaris. We performed Tc-99m DPD serial bone scanning to monitor the course of disease and to assess therapeutic efficiency. Control bone scans in 2001 showed minor compromises of the ribs and diminished disease activity on collarbones and the sternum after medication with non-steroidal anti-inflammatory drugs (NSAIDs) and bisphosphonates. F-18 FDG PET presented synovial inflammation in the left sterno-clavicular joint but no relevant tracer uptake on clavicles or breastbones. In case of diagnostic doubts F-18 FDG PET could be recommended in order to discriminate bland osteomyelitis from bacterial osteomyelitis or from bone malignancy when SAPHO-syndrome is assumed. |
| Databáze: | OpenAIRE |
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