THE EVALUATION OF METHODS FOR DETERMINATIONS OF URINARY OXALATE
| Autor: | Kazushiro Takei, Haruo Ito, Koichiro Akakura, Takeshi Ueda, Ken-ichi Egoshi |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Oxalates Chromatography Adolescent Calcium Oxalate Spectrum Analysis Urology Urinary system Ion chromatography Urine Middle Aged Chromatography Ion Exchange Sensitivity and Specificity Oxalate Excretion chemistry.chemical_compound chemistry Evaluation Studies as Topic Urine oxalate Humans Colorimetry Female Urinary Calculi Aged |
| Zdroj: | The Japanese Journal of Urology. 90:675-680 |
| ISSN: | 1884-7110 0021-5287 |
| DOI: | 10.5980/jpnjurol1989.90.675 |
| Popis: | BACKGROUND Estimation of urinary oxalate is one of important tools for the diagnosis and treatment of urolithiasis. And more precise, simple and inexpensive method is desirable. In the present study, we evaluated three methods which were clinically well-used. METHODS From October 1996 to June 1997, 146 acidified urine samples were collected for 24 hours from 144 urolithiasis patients. We determined the urinary oxalates by three methods; the colorimetric method, the enzymic method and the ion chromatography (IC method). And we evaluated the correlations of these methods. RESULTS Correlation coefficients in the urine oxalate concentration were, 0.86 with the colorimetric method and the IC method, 0.91 with the enzymic method and the IC method, 0.90 with the colorimetric method and the enzymic method. The coefficients in the 24 hours-urinary excretion of oxalate (0.76, 0.87, 0.82) were lower than those in the urine oxalate concentration. The correlation coefficients with the colorimetric method and the IC method were, 0.58 in hyperoxaluric group, 0.34 in normooxaluric group. The coefficients with the enzymic method and the IC method, 0.93 in hyperoxaluric group, 0.71 in normooxaluric group. CONCLUSION The colorimetric method is least expensive, but is less useful. The enzymic method is less expensive, and is as useful as the IC method. |
| Databáze: | OpenAIRE |
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