Excellent Response to OnabotulinumtoxinA : Different Definitions, Different Predictors

Autor: Ornello, Raffaele, Baraldi, Carlo, Ahmed, Fayyaz, Negro, Andrea, Miscio, Anna Maria, Santoro, Antonio, Alpuente, Alicia, Russo, Antonio, Silvestro, Marcello, Cevoli, Sabina, Brunelli, Nicoletta, Vernieri, Fabrizio, Grazzi, Licia, Pani, Luca, Andreou, Anna P, Lambru, Giorgio, Frattale, Ilaria, Kamm, Katharina, Ruscheweyh, Ruth, Russo, Marco, Torelli, Paola, Filatova, Elena, Latysheva, Nina, Gryglas-Dworak, Anna, Straburzyński, Marcin, Butera, Calogera, Colombo, Bruno, Filippi, Massimo, Pozo-Rosich, Patricia, Martelletti, Paolo, Guerzoni, Simona, Sacco, Simona, Universitat Autònoma de Barcelona
Přispěvatelé: Ornello, Raffaele, Baraldi, Carlo, Ahmed, Fayyaz, Negro, Andrea, Miscio, Anna Maria, Santoro, Antonio, Alpuente, Alicia, Russo, Antonio, Silvestro, Marcello, Cevoli, Sabina, Brunelli, Nicoletta, Vernieri, Fabrizio, Grazzi, Licia, Pani, Luca, Andreou, Anna, Lambru, Giorgio, Frattale, Ilaria, Kamm, Katharina, Ruscheweyh, Ruth, Russo, Marco, Torelli, Paola, Filatova, Elena, Latysheva, Nina, Gryglas-Dworak, Anna, Straburzyński, Marcin, Butera, Calogera, Colombo, Bruno, Filippi, Massimo, Pozo-Rosich, Patricia, Martelletti, Paolo, Guerzoni, Simona, Sacco, Simona, Institut Català de la Salut, [Ornello R] Neuroscience Section, Department of Applied Clinical Sciences and Biotechnology, University of L’Aquila, L’Aquila, Italy. [Baraldi C] Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, Department of Specialist Medicines, AOU Policlinico di Modena, Modena, Italy. [Ahmed F] Department of Neurosciences, Hull University Teaching Hospitals, Hull, UK. [Negro A] Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant’Andrea Hospital, Sapienza University, Rome, Italy. [Miscio AM, Santoro A] Headache Center, Unit of Neurology, Fondazione IRCCS 'Casa Sollievo Della Sofferenza', San Giovanni Rotondo, Italy. [Alpuente A, Pozo-Rosich P] Unitat de Cefalea, Servei de Neurologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Cefalea i Dolor Neurològic, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus
Jazyk: angličtina
Rok vydání: 2022
Předmět:
chronic migraine
onabotulinumtoxinA
predictors of response
excellent responders
Botulinum Toxins
enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades cerebrales::trastornos con cefaleas::cefaleas primarias::trastornos migrañosos [ENFERMEDADES]
Health
Toxicology and Mutagenesis

Migraine Disorders
Excellent responders
acciones y usos químicos::acciones tóxicas::noxas::neurotoxinas [COMPUESTOS QUÍMICOS Y DROGAS]
Predictors of response
Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]
Migranya - Tractament
Other subheadings::Other subheadings::/drug therapy [Other subheadings]
Type A
Neurotoxines - Ús terapèutic
Humans
Chemical Actions and Uses::Toxic Actions::Noxae::Neurotoxins [CHEMICALS AND DRUGS]
Other subheadings::/therapeutic use [Other subheadings]
Botulinum Toxins
Type A

Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Headache Disorders::Headache Disorders
Primary::Migraine Disorders [DISEASES]

Chronic migraine
Otros calificadores::/uso terapéutico [Otros calificadores]
Chronic Disease
Female
Headache
Treatment Outcome
Public Health
Environmental and Occupational Health

Onabotulinumtoxina
Avaluació de resultats (Assistència sanitària)
Zdroj: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Ornello, R, Baraldi, C, Ahmed, F, Negro, A, Miscio, A M, Santoro, A, Alpuente, A, Russo, A, Silvestro, M, Cevoli, S, Brunelli, N, Vernieri, F, Grazzi, L, Pani, L, Andreou, A, Lambru, G, Frattale, I, Kamm, K, Ruscheweyh, R, Russo, M, Torelli, P, Filatova, E, Latysheva, N, Gryglas-Dworak, A, Straburzyński, M, Butera, C, Colombo, B, Filippi, M, Pozo-Rosich, P, Martelletti, P, Guerzoni, S & Sacco, S 2022, ' Excellent Response to OnabotulinumtoxinA: Different Definitions, Different Predictors ', International Journal of Environmental Research and Public Health, vol. 19, no. 17, pp. 10975 . https://doi.org/10.3390/ijerph191710975
International Journal of Environmental Research and Public Health; Volume 19; Issue 17; Pages: 10975
Scientia
DOI: 10.3390/ijerph191710975
Popis: Chronic migraine; OnabotulinumtoxinA; Predictors of response Migraña crónica; OnabotulinumtoxinA; Predictores de respuesta Migranya crònica; OnabotulinumtoxinA; Predictors de resposta The identification of patients who can benefit the most from the available preventive treatments is important in chronic migraine. We explored the rate of excellent responders to onabotulinumtoxinA in a multicenter European study and explored the predictors of such response, according to different definitions. A pooled analysis on chronic migraineurs treated with onabotulinumtoxinA and followed-up for, at least, 9 months was performed. Excellent responders were defined either as patients with a ≥75% decrease in monthly headache days (percent-based excellent responders) or as patients with
Databáze: OpenAIRE