An Unprecedented Biogenetic-Type Chemical Synthesis of 1(15→11) Abeotaxanes from Normal Taxanes
| Autor: | Kandikonda Rajendar, Vinay Kr. Singh, K. Papi Reddy, Jayanta Sarkar, Tadigoppula Narender |
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| Rok vydání: | 2010 |
| Předmět: |
Pharmacology
Molecular Structure Paclitaxel Stereochemistry Organic Chemistry Pharmaceutical Science Chemical synthesis Analytical Chemistry chemistry.chemical_compound Complementary and alternative medicine chemistry One pot reaction Drug Discovery Molecular Medicine Taxoids Diterpene Nuclear Magnetic Resonance Biomolecular Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Journal of Natural Products. 73:747-750 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np900722j |
| Popis: | A one-pot chemical process using BF(3).Et(2)O for the synthesis of a new class of 1(15--11) abeotaxanes from normal taxanes has been developed. The chemical structures of rearranged 1(15--11) abeotaxane were established by extensive 2D NMR spectroscopic data. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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