Colony formation by primitive haemopoietic progenitors in cocultures of bone marrow cells and stromal cells
| Autor: | Lyndal Kearney, J. M. Goldman, Myrtle Y. Gordon, Edward C. Gordon-Smith, J. A. Hibbin |
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| Rok vydání: | 1985 |
| Předmět: |
Time Factors
Stromal cell Cell Survival CD34 Bone Marrow Cells Hematology Biology Hematopoietic Stem Cells In vitro Cell biology Colony-Forming Units Assay Endothelial stem cell medicine.anatomical_structure Antigen Precursor cell Cell Adhesion medicine Humans Hydroxyurea Bone marrow Progenitor cell Cells Cultured |
| Zdroj: | British Journal of Haematology. 60:129-136 |
| ISSN: | 1365-2141 0007-1048 |
| DOI: | 10.1111/j.1365-2141.1985.tb07393.x |
| Popis: | Summary Human bone marrow contains a class of human haemopoietic progenitor cells that adhere to cultured marrow stromal cells and form colonies of blast cells. These progenitor cells are found in the non-adherent mononuclear fraction of normal human bone marrow. They are not in active cell cycle and do not express Ia-like (HLA-DR) antigens but appear to be capable of self-renewal in vitro. These properties indicate that they should be classified as members of the primitive haemopoietic progenitor cell compartment. |
| Databáze: | OpenAIRE |
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