Skin insertion site culture for the prediction of primary bloodstream infection
| Autor: | María Lecuona, María L. Mora, Leonardo Lorente, Alejandro Jiménez, Adriana González-Mesa, Manuel Callejon, Ana Madueño, Alejandra Pérez-Llombet |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment New episode Insertion site Bacteremia 030204 cardiovascular system & hematology Bloodstream infection law.invention Sepsis 03 medical and health sciences 0302 clinical medicine law Internal medicine Medicine Central Venous Catheters Humans 030212 general & internal medicine Prospective Studies Prospective cohort study business.industry General Medicine medicine.disease Predictive value Intensive care unit Catheter-Related Infections Original Article business Prediction Central venous catheter Skin insertion site culture |
| Zdroj: | Irish Journal of Medical Science |
| ISSN: | 1863-4362 0021-1265 |
| Popis: | Purpose Previous studies have analyzed the capability of skin insertion site culture to predict catheter-related bloodstream infection (CRBSI). However, there has been not analyzed its capability to predict primary bloodstream infection (PBSI), that include CRBSI and bloodstream infection of unknown origin (BSIUO). The novel objective of our study was to determine the capability of insertion skin site culture to predict CRBSI and primary bloodstream infection (PBSI), that include CRBSI and bloodstream infection of unknown origin (BSIUO). Material and methods Observational and prospective study in one Intensive Care Unit. Patients with some central venous catheter (CVC) at least during 7 days and suspected catheter-related infection (CRI) (new episode of fever or sepsis) were included. Cultures of insertion skin site, paired blood samples, catheter-tip, and other clinical samples were taken. Capability of insertion skin site culture to predict CRBSI and PBSI was determined. Results We included 108 CVC from 96 CRI suspicion episodes. The causes that motivated CRI suspicion were 20 (18.5%) PBSI, 44 (40.7%) other infections, and 44 (40.7%) unknown. Among the 20 PBSI, 11 (55%) were CRBSI and 9 (45%) were BSIUO. Negative predictive value of insertion skin site culture to predict CRBSI was 95% (87–98%) and to predict PBSI was 85% (76–91%). Conclusions The new finding of our study was that skin insertion site culture had a good negative predicted valued for the prediction of CRBSI and PBSI. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink