Hemodynamics of the diastolic pressure gradients in acute heart failure: implications for the diagnosis of pre-capillary pulmonary hypertension in left heart disease
| Autor: | Andrew J. Burger, Doron Aronson, Emilia Hardak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system heart failure Hemodynamics 030204 cardiovascular system & hematology hemodynamics 03 medical and health sciences 0302 clinical medicine Internal medicine pulmonary hypertension medicine skin and connective tissue diseases lcsh:RC705-779 business.industry lcsh:Diseases of the respiratory system medicine.disease Pulmonary hypertension Blood pressure 030228 respiratory system lcsh:RC666-701 Heart failure Cardiology sense organs Left heart disease diastolic pulmonary vascular pressure gradient business Research Article |
| Zdroj: | Pulmonary Circulation, Vol 9 (2018) Pulmonary Circulation |
| ISSN: | 2045-8940 |
| Popis: | The diastolic pressure gradient (DPG) has been proposed as the metric of choice for the diagnosis of pulmonary vascular changes in left heart disease. We tested the hypothesis that this metric is less sensitive to changes in left atrial pressure and stroke volume (SV) than the transpulmonary gradient (TPG). We studied the effect of dynamic changes in pulmonary capillary wedge pressure (PCWP), SV, and pulmonary artery capacitance (PAC) on DPG and TPG in 242 patients with acute heart failure undergoing decongestive therapy with continuous hemodynamic monitoring. There was a close impact of PCWP reduction on TPG and DPG, with a 0.13 mmHg (95% confidence interval [CI] 0.07–0.19, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text