Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism
| Autor: | David S. Ludwig, Bridget M. Hron, Cara B. Ebbeling, Henry A. Feldman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.drug_class Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Amylin 030209 endocrinology & metabolism lcsh:TX341-641 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Weight loss Internal medicine Adipocyte medicine Chemerin lcsh:RC620-627 Pancreatic hormone 2. Zero hunger Nutrition and Dietetics biology Bile acid FGF-21 Research Dietary composition Insulin sensitivity lcsh:Nutritional diseases. Deficiency diseases 030104 developmental biology Endocrinology chemistry Metabolic hormones biology.protein Ghrelin Energy expenditure medicine.symptom lcsh:Nutrition. Foods and food supply Hormone |
| Zdroj: | Nutrition & Metabolism Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-7 (2017) |
| ISSN: | 1743-7075 0031-5354 |
| Popis: | We sought to characterize the effects of dietary macronutrient composition on various hormones implicated in the regulation of insulin sensitivity (IS) and energy expenditure (EE). Following 10–15% weight loss, 21 overweight subjects consumed 3 weight-loss maintenance diets [low fat (LF), low glycemic index (LGI) and very low carbohydrate (VLC)] in random order, each for 4 weeks. At baseline and at the end of each treatment period, fasting samples for fibroblast growth factor (FGF)-21, heme-oxygenase-1 (HO-1), chemerin, irisin, secreted frizzle-related protein (SFRP-4), total bile acids, ghrelin, gastrin inhibitory peptide (GIP), peptide-Y, and amylin; hepatic and peripheral IS; and EE were obtained. Analyses were controlled for age, gender, baseline body mass index, and diet sequence. FGF-21 decreased (P |
| Databáze: | OpenAIRE |
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