Source attributed case-control study of campylobacteriosis in New Zealand
| Autor: | Jillian Sherwood, Nigel P. French, Anne C. Midwinter, E. Ashmore, P. Shoemack, Jonathan C. Marshall, Michael G Baker, Robin J. Lake, Donald Campbell, David A. Wilkinson, S. Pirikahu, B.J. Horn, Jackie Benschop, P.J. Cressey, Steve Hathaway |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Male Rural Population Food Safety Meat Urban Population Case control 030106 microbiology Campylobacteriosis Biology Campylobacter jejuni Poultry lcsh:Infectious and parasitic diseases 03 medical and health sciences Feces 0302 clinical medicine Risk Factors Environmental health Campylobacter Infections medicine Animals Humans lcsh:RC109-216 030212 general & internal medicine Significant risk Aged Sheep Case-control study Infant General Medicine Odds ratio medicine.disease biology.organism_classification Bacterial Typing Techniques Infectious Diseases Case-Control Studies Source attributed Multilocus sequence typing Cattle Female Rural area Urban centre Multilocus Sequence Typing New Zealand |
| Zdroj: | International Journal of Infectious Diseases, Vol 103, Iss, Pp 268-277 (2021) |
| ISSN: | 1878-3511 |
| Popis: | Background Following an initial reduction in human campylobacteriosis in New Zealand after the implementation of poultry food chain-focused interventions during 2006–2008, further decline has been relatively small. We report a year-long study of notified campylobacteriosis cases, incorporating a case control study combined with a source attribution study. The purpose was to generate up-to-date evidence on the relative contributions of different sources of campylobacteriosis in New Zealand. Methods The study approach included: • A case-control study of notified cases (aged six months or more) sampled in a major urban centre (Auckland, every second case) and a mixed urban/rural area (Manawatū/Whanganui, every case), between 12 March 2018 and 11 March 2019. • Source attribution of human campylobacteriosis cases sampled from these two regions over the study period by modelling of multilocus sequence typing data of Campylobacter jejuni and C. coli isolates from faecal samples of notified human cases and relevant sources (poultry, cattle, sheep). Results Most cases (84%) were infected with strains attributed to a poultry source, while 14% were attributed to a cattle source. Approximately 90% of urban campylobacteriosis cases were attributed to poultry sources, compared to almost 75% of rural cases. Poultry consumption per se was not identified as a significant risk factor. However specific risk factors related to poultry meat preparation and consumption did result in statistically significantly elevated odds ratios. Conclusions The overall findings combining source attribution and analysis of specific risk factors indicate that poultry meat remains a dominant pathway for exposure and infection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|