Can the Expanded Disability Status Scale be assessed by telephone?
| Autor: | Robert W. Gibberd, Jeannette Lechner-Scott, Maria Pia Amato, C Buttinelli, M Hofman, M Versavel, Xavier Montalban, Mar Tintoré, Chris H. Polman, M. Frontoni, Maria Letizia Bartolozzi, H Ronner, Frank Dahlke, L Kappos, J F Kapp |
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| Přispěvatelé: | University of Zurich, Kappos, L |
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Intraclass correlation 610 Medicine & health Neurological examination Physical examination Walking Interviews as Topic Disability Evaluation 03 medical and health sciences 0302 clinical medicine Humans Medicine 030212 general & internal medicine Aged Expanded Disability Status Scale medicine.diagnostic_test business.industry Telephone call Reproducibility of Results 11359 Institute for Regenerative Medicine (IREM) Middle Aged Surgery Europe Clinical trial 2728 Neurology (clinical) Neurology Telephone interview 2808 Neurology Physical therapy Female Neurology (clinical) business 030217 neurology & neurosurgery Kappa |
| Zdroj: | Multiple Sclerosis Journal. 9:154-159 |
| ISSN: | 1477-0970 1352-4585 |
| DOI: | 10.1191/1352458503ms884oa |
| Popis: | Information from patients who are unable to continue their visits to a study centre may be of major importance for the interpretatio n of results in multiple sclerosis (MS) clinical trials. To validate a questionnaire based on the Expanded Disability Status Scale (EDSS), patients in five different European centres were assessed independently by pairs of trained EDSS raters, first by telepho ne interview and a few days later by standardized neurological examination. Seventy women and 40 men with an average age of 43.7 years (range 19 -74 years) were included in the study. Mean EDSS score at the last visit was 4.5 (0 -9). EDSS assessment by telepho ne was highly correlated with the EDSS determined by physical examination (Pearson’s correlation coefficient -0.95). A n intraclass correlation coefficient (IC C) of 94.8% was found for the total sample; 77.6% and 86%, respectively, for patients with EDSSB-4.5 (n -46) and \-4.5 (n -64). Kappa values for full agreement were 0.48; for variation by -0.5 steps and -1.0 steps, 0.79 and 0.90, respectively. Best agreement could be found in higher EDSS scores, where assessment by telepho ne interview might be needed most. The telepho ne questionnaire is a valid tool to assess EDSS score in cases where the patient is unable to continue visiting a study centre or in long-term follow-up of trial participants. |
| Databáze: | OpenAIRE |
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