Association between Low-density lipoprotein cholesterol and occipital periventricular hyperintensities in a group of Chinese patients: an observational study
| Autor: | Dazhi Duan, Chun Cui, Lin Shen, Tongsheng Shu, Jian Zheng |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Clinical chemistry Endocrinology Diabetes and Metabolism Clinical Biochemistry Low density lipoprotein cholesterol Clinical nutrition 030204 cardiovascular system & hematology Occipital periventricular hyperintensities Gastroenterology Cardiovascular risk factor 03 medical and health sciences 0302 clinical medicine Endocrinology Asian People Internal medicine medicine White matter hyperintensity Humans Low-density lipoprotein cholesterol Aged Biochemistry medical Univariate analysis business.industry Research Biochemistry (medical) Age Factors Cholesterol LDL Magnetic Resonance Imaging Hyperintensity Case-Control Studies Multivariate Analysis Observational study lipids (amino acids peptides and proteins) Occipital Lobe business 030217 neurology & neurosurgery Lipidology MRI |
| Zdroj: | Lipids in Health and Disease |
| ISSN: | 1476-511X |
| Popis: | Background While occipital periventricular hyperintensities (OPVHs) are among the most common mild white matter hyperintensities, the clinical factors associated with OPVHs remain unclear. In this study, we investigated the role of clinical factors in development of pure OPVHs. Methods This study included 97 patients with OPVHs and 73 healthy controls. Univariate analysis of clinical factors in OPVH patients and controls was followed by binomial logistic regression analysis to identify clinical factors significantly associated with OPVHs. Result Univariate analysis indicated that age, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and apolipoprotein-B (Apo-B) levels differed significantly between the OPVH patients and controls (p |
| Databáze: | OpenAIRE |
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