Influence of electromagnetic pulse on the offspring sex ratio of male BALB/c mice
| Autor: | Junye Liu, Sheng-Long Xu, Hai-yang Lang, Jin-hui Li, Jia-jia Yan, Xia Miao, Guo-Zhen Guo, Qi-yan Guo, Da-peng Jiang, Ya-feng Wang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Offspring Health Toxicology and Mutagenesis Toxicology BALB/c Gonadotropin-Releasing Hormone 03 medical and health sciences Electromagnetic Fields 0302 clinical medicine Internal medicine medicine Animals Testosterone Sex Ratio Pharmacology Mice Inbred BALB C 030219 obstetrics & reproductive medicine biology Reproduction Radioimmunoassay General Medicine Luteinizing Hormone biology.organism_classification Paternal Exposure 030104 developmental biology Endocrinology Agarose gel electrophoresis Female Sex ratio Hormone |
| Zdroj: | Environmental Toxicology and Pharmacology. 54:155-161 |
| ISSN: | 1382-6689 |
| DOI: | 10.1016/j.etap.2017.06.015 |
| Popis: | Public concern is growing about the exposure to electromagnetic fields (EMF) and its effect on male reproductive health. Detrimental effect of EMF exposure on sex hormones, reproductive performance and sex-ratio was reported. The present study was designed to clarify whether paternal exposure to electromagnetic pulse (EMP) affects offspring sex ratio in mice. 50 male BALB/c mice aged 5-6 weeks were exposed to EMP daily for 2 weeks before mated with non-exposed females at 0d, 7d, 14d, 21d and 28d after exposure. Sex hormones including total testosterone, LH, FSH, and GnRH were detected using radioimmunoassay. The sex ratio was examined by PCR and agarose gel electrophoresis. The results of D0, D21 and D28 showed significant increases compared with sham-exposed groups. The serum testosterone increased significantly in D0, D14, D21, and D28 compared with sham-exposed groups (p |
| Databáze: | OpenAIRE |
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