Microglia extracellular traps in Oreochromis niloticus infected with Weissella cibaria
| Autor: | Pedro Galdino de Souza, Fabíola Christian Almeida de Carvalho, Marco Antonio de Andrade Belo, João Victor da Costa Alecrim, João Martins Pizauro, Dayanne Carla Fernandes, Silas Fernandes Eto, Michelli Inácio Gonçalves Funnicelli |
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| Přispěvatelé: | Federal University of Roraima (UFRR), (CeTICS/FAPESP), Universidade Estadual Paulista (Unesp), University of Brazil |
| Rok vydání: | 2021 |
| Předmět: |
Lipopolysaccharides
0301 basic medicine Extracellular Traps Lipopolysaccharide Aquatic Science Microbiology Fish Diseases 03 medical and health sciences Nile tilapia chemistry.chemical_compound Neuroinflammation medicine Animals Environmental Chemistry Meningitis Weissella cibaria Gram-Positive Bacterial Infections ETs biology Microglia Nitric oxide Cichlids 04 agricultural and veterinary sciences General Medicine biology.organism_classification In vitro Oreochromis 030104 developmental biology medicine.anatomical_structure chemistry Weissella Microscopy Electron Scanning 040102 fisheries 0401 agriculture forestry and fisheries |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1050-4648 |
| DOI: | 10.1016/j.fsi.2021.03.020 |
| Popis: | Made available in DSpace on 2021-06-25T10:57:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) The mechanism of extracellular traps (ETs) is important in the cellular response against bacteria. Thus, in the present study, we describe for the first time the capacity of the Nile tilapia (Oreochromis niloticus) microglia in the formation of ETs in Weissella cibaria in vitro infection. Thus, we evaluated the ultrastructure of the microglia culture and observed the formation of ETs 6 h after stimulation with lipopolysaccharide (LPS) and during the course of infection. Our results shed light on the mechanism of formation of ETs in the microglia of teleost fish and the ability of W. cibaria to infect these cells. Department of Postgraduate in Health Sciences-PROCISA Federal University of Roraima (UFRR) Immunochemistry Laboratory Butantan Institute (CeTICS/FAPESP) Department of Technology School of Agrarian and Veterinary Sciences Sao Paulo State University (Unesp) Laboratory of Animal Pharmacology and Toxicology University of Brazil, Descalvado Department of Preventive Veterinary Medicine of Unesp School of Agrarian and Veterinary Sciences São Paulo State University (Unesp), Jaboticabal Department of Technology School of Agrarian and Veterinary Sciences Sao Paulo State University (Unesp) Department of Preventive Veterinary Medicine of Unesp School of Agrarian and Veterinary Sciences São Paulo State University (Unesp), Jaboticabal |
| Databáze: | OpenAIRE |
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