Value of shear wave elastography combined with the Toronto clinical scoring system in diagnosis of diabetic peripheral neuropathy
| Autor: | Tong Chen, Meng Wang, Ji Hu, Honghong Zhang, Xin Song, Qi Ma, Miao Zheng, Chen Fang, Fei Wang, Yunyan Zhu |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Scoring system Observational Study Humans Medicine Cutoff Diabetic Nephropathies In patient Toronto clinical scoring system Tibial nerve Aged shear wave elastography Shear wave elastography Receiver operating characteristic business.industry diabetic peripheral neuropathy Area under the curve Peripheral Nervous System Diseases Reproducibility of Results General Medicine Middle Aged medicine.disease Peripheral neuropathy Diabetes Mellitus Type 2 ROC Curve Research Design cross-sectional area Elasticity Imaging Techniques Female business Nuclear medicine Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000027104 |
| Popis: | To evaluate the diagnostic values of shear wave elastography (SWE) alone and in combination with the Toronto clinical scoring system (TCSS) on diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM). The study included 41 DPN patients, 42 non-DPN patients, and 21 healthy volunteers. Conventional ultrasonography and SWE were performed on the 2 sides of the tibial nerves, and cross-sectional area (CSA) and nerve stiffness were measured. TCSS was applied to all patients. A receiver operating characteristic curve analysis was performed. The stiffness of the tibial nerve, as measured as mean, minimum or maximum elasticity, was significantly higher in patients in the DPN group than the other groups (P .05). Mean elasticity of the tibial nerve with a cutoff of 71.3 kPa was the most sensitive (68.3%) and had a higher area under the curve (0.712; 0.602–0.806) among the 3 shear elasticity indices for diagnosing DPN when used alone. When combining SWE with TCSS in diagnosing DPN, the most effective parameter was the EMax, which yielded a sensitivity of 100.00% and a specificity of 95.24%. SWE is a better diagnostic tool for DPN than the conventional ultrasonic parameter CSA, and a higher diagnostic value is attained when combining SWE with TCSS. |
| Databáze: | OpenAIRE |
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