Shared functional connectivity between the dorso-medial and dorso-ventral streams in macaques
| Autor: | Hansjörg Scherberger, Ramina Adam, R. Stefan Greulich, Stefan Everling |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male Mediodorsal Thalamic Nucleus Movement Precuneus lcsh:Medicine Intraparietal sulcus Biology Insular cortex Article Premotor cortex 03 medical and health sciences 0302 clinical medicine Sensorimotor processing Motor control Neural Pathways medicine Psychology Animals lcsh:Science Brain Mapping Multidisciplinary Resting state fMRI Hand Strength lcsh:R Neurosciences Motor Cortex Precentral gyrus Hand Central sulcus Macaca mulatta Magnetic Resonance Imaging 030104 developmental biology medicine.anatomical_structure Sensory processing lcsh:Q Sensorimotor Cortex Primary motor cortex Neuroscience 030217 neurology & neurosurgery Psychomotor Performance |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020) Scientific Reports Brain and Mind Institute Researchers' Publications |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-75219-x |
| Popis: | Manipulation of an object requires us to transport our hand towards the object (reach) and close our digits around that object (grasp). In current models, reach-related information is propagated in the dorso-medial stream from posterior parietal area V6A to medial intraparietal area, dorsal premotor cortex, and primary motor cortex. Grasp-related information is processed in the dorso-ventral stream from the anterior intraparietal area to ventral premotor cortex and the hand area of primary motor cortex. However, recent studies have cast doubt on the validity of this separation in separate processing streams. We investigated in 10 male rhesus macaques the whole-brain functional connectivity of these areas using resting state fMRI at 7-T. Although we found a clear separation between dorso-medial and dorso-ventral network connectivity in support of the two-stream hypothesis, we also found evidence of shared connectivity between these networks. The dorso-ventral network was distinctly correlated with high-order somatosensory areas and feeding related areas, whereas the dorso-medial network with visual areas and trunk/hindlimb motor areas. Shared connectivity was found in the superior frontal and precentral gyrus, central sulcus, intraparietal sulcus, precuneus, and insular cortex. These results suggest that while sensorimotor processing streams are functionally separated, they can access information through shared areas. |
| Databáze: | OpenAIRE |
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