The diagnostic ability of core needle biopsy in nodular thyroid disease

Autor: Ozgor M, Coci K, Beril Guler, Kadakal G, Erhan Aysan, Ufuk Oguz Idiz, Sema Arici, Enver Kunduz, Huseyin Akbulut, Tugce Kiran
Přispěvatelé: KIRAN, Tuğçe
Rok vydání: 2017
Předmět:
Adult
Image-Guided Biopsy
Male
Thyroid nodules
medicine.medical_specialty
Adolescent
medicine.medical_treatment
030209 endocrinology & metabolism
Thyroid Carcinoma
Anaplastic

Young Adult
03 medical and health sciences
0302 clinical medicine
Biopsy
medicine
Carcinoma
Humans
Endocrine Surgery
Aysan E.
KIRAN T.
IDIZ U.
GULER B.
AKBULUT H.
KUNDUZ E.
ARICI S.
KADAKAL G.
Ozgor M.
Coci K.
-The diagnostic ability of core needle biopsy in nodular thyroid disease.-
Annals of the Royal College of Surgeons of England
cilt.99
ss.233-236
2017

Thyroid Neoplasms
Thyroid Nodule
Aged
Ultrasonography
Aged
80 and over

medicine.diagnostic_test
business.industry
Thyroid
Thyroidectomy
Nodule (medicine)
General Medicine
Middle Aged
medicine.disease
Carcinoma
Papillary

Carcinoma
Neuroendocrine

Surgery
Fine-needle aspiration
medicine.anatomical_structure
Thyroid Cancer
Papillary

030220 oncology & carcinogenesis
Female
Biopsy
Large-Core Needle

Radiology
medicine.symptom
business
Popis: INTRODUCTION Non-diagnostic results of fine needle aspiration biopsy (FNAB) remain an important limitation of this technqiue. The aim of our study was to evaluate the results of core needle biopsy (CNB) of thyroid nodules and its effectiveness in non-diagnostic FNAB cases. METHODS CNBs were performed in 1,000 patients (154 male, 846 female; mean age: 50.2 years, range: 18–86 years) with a spring loaded 20G needle. Of these, 143 had initially had FNABs that were insufficient for evaluation. The CNB reports were reviewed. Patients with suspicious or malignant CNB results underwent total thyroidectomy. RESULTS When considering all 1,000 CNBs, the non-diagnostic rate was 1.5% (15/1,000). However, when the first 100 cases were eliminated as a learning curve, this reduced to 0.9% (8/900). Of the 143 cases with initial FNABs that were non-diagnostic, 0.7% (1/143) were also non-diagnostic on CNB. Twelve patients underwent surgery because of malignant CNB reports and all of these cases were confirmed as malignant by the postoperative pathology specimen results (100% accuracy). There were no major complications although three self-limiting minor complications were observed. CONCLUSIONS CNB is a safe and accurate method. It is more diagnostic than FNAB for nodular thyroid disease.
Databáze: OpenAIRE