Dapsone for thrombocytopenic purpura related to human immunodeficiency virus infection

Autor: Patrice Lefevre, Maurice Mongin, Philippe Hovette, Jean Marc Durand, Soumana Issifi
Rok vydání: 1991
Předmět:
Zdroj: The American journal of medicine. 90(6)
ISSN: 0002-9343
Popis: purpose: The purpose of this study was to determine the effect of dapsone on platelet count in patients with human immunodeficiency virus (HIV)-related autoimmune thrombocytopenia. patients And Methods:Eleven patients with HIV-related thrombocytopenia received dapsone (50 to 125 mg/day) for 2 to 43 months. Patients with the acquired immunodeficiency syndrome were not enrolled. results: Of the 11 patients, six developed platelet counts above 50 × 10 9 /L and did not require any other specific therapy. No significant side effects were observed. conclusion: We conclude that dapsone may be effective in some patients with HIV-related thrombocytopenia.
Databáze: OpenAIRE