Synthesis of sterically controlled chiral β-amino alcohols and their application to the catalytic asymmetric sulfoxidation of sulfides
| Autor: | Yong-Chul Jeong, Soojin Choi, Yao Dong Huang, Kwang-Hyun Ahn |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Steric effects
chemistry.chemical_classification organic chemicals Aryl Organic Chemistry Enantioselective synthesis Vanadium chemistry.chemical_element General Medicine Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry polycyclic compounds Organic chemistry heterocyclic compounds Physical and Theoretical Chemistry Menthol Alkyl |
| Zdroj: | Tetrahedron: Asymmetry. 16:3497-3501 |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2005.07.035 |
| Popis: | Sterically hindered and enantiomerically pure β-amino alcohols 8a and 8b were prepared from the enantiomerically pure aziridine-2-carboxylic acid menthol ester 13. Vanadium complexes of the chiral Schiff-base ligands prepared from the β-amino alcohols catalyze an efficient enantioselective sulfoxidation of alkyl aryl sulfides, while enantioselectivities as high as 96% ee can be observed in the sulfoxidation of benzyl aryl sulfides. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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