Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis?
| Autor: | Pascal Lim, Raphaelle Huguet, Vania Tacher, Remi Valter, Amina Moussafeur, Thierry Folliguet, Virgile Chevance, Islem Sifaoui, Mohamed Refaat Nouri, Sebastien Mule, Florence Canoui-Poitrine, Eric Bergoend, Raphael Lepeule, Jean-François Deux |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Atypical bacteria Cardiac computed tomography business.industry cardiac imaging techniques Mortality rate endocarditis bacterial valve calcium scoring General Medicine medicine.disease Article Embolism Infective endocarditis Internal medicine Cardiology cardiovascular system Medicine In patient Aortic calcifications cardiovascular diseases business cardiac computed tomography Calcium score |
| Zdroj: | Journal of Clinical Medicine, Vol 10, Iss 4458, p 4458 (2021) Journal of Clinical Medicine Volume 10 Issue 19 |
| ISSN: | 2077-0383 |
| Popis: | Background: Evaluate the impact of valvular calcifications measured on cardiac computed tomography (CCT) in patients with infective endocarditis (IE). Methods: Seventy patients with native IE (36 aortic IE, 31 mitral IE, 3 bivalvular IE) were included and explored with CCT between January 2016 and April 2018. Mitral and aortic valvular calcium score (VCS) were measured on unenhanced calcium scoring images, and correlated with clinical, surgical data, and 1-year death rate. Results: VCS of patients with mitral IE and no peripheral embolism was higher than those with peripheral embolism (868 (25–1725) vs. 6 (0–95), p < 0.05). Patients with high calcified mitral IE (mitral VCS > 100 n = 15) had a lower rate of surgery (40.0% vs.78.9% p = 0.03) and a higher 1-year-death risk (53.3% vs. 10.5%, p = 0.04 OR = 8.5 (2.75–16.40) than patients with low mitral VCS (n = 19). Patients with aortic IE and high aortic calcifications (aortic VCS > n = 18) present more frequently atypical bacteria on blood cultures (33.3% vs. 4.8% p = 0.03) than patients with low aortic VCS (n = 21). Conclusion: The amount of valvular calcifications on CT was associated with embolism risk, rate of surgery and 1-year risk of death in patients with mitral IE, and germ’s type in aortic IE raising the question of their systematic quantification in native IE. |
| Databáze: | OpenAIRE |
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