Infra-red tomography of port-wine-stain blood vessels in human skin
| Autor: | M. J. C. Van Gemert, Dennis M. Goodman, Thomas E. Milner, J.S. Nelson, B. S. Tanenbaum |
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| Rok vydání: | 1996 |
| Předmět: |
infra-red tomography
laser treatment Materials science port-wine stain Biomedical Engineering Human skin Dermatology law.invention Optics blood vessel law photothermolysis medicine Absorption (electromagnetic radiation) Tomographic reconstruction business.industry Dermatology & Venereal Diseases Port-wine stain Photothermal therapy medicine.disease Laser medicine.anatomical_structure Surgery Tomography business Blood vessel |
| Zdroj: | Nelson, JS; Milner, TE; Tanenbaum, BS; Goodman, DM; & Van Gemert, MJC. (1996). Infra-red tomography of port-wine-stain blood vessels in human skin. Lasers in Medical Science, 11(3), 199-204. doi: 10.1007/BF02156765. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0g22q74z |
| ISSN: | 1435-604X 0268-8921 |
| DOI: | 10.1007/bf02156765 |
| Popis: | Specifying the distribution of laser energy within a tissue is the first step towards understanding and capitalizing on a variety of laser-tissue interactions. Whether photothermal, photochemical or photomechanical in nature, laser-tissue interactions begin with the absorption of photon energy. The spatial distribution of photon absorption specifies the required laser exposure to be delivered and the extent of subsequent therapeutic action. Using infra-red tomography (IRT), the broad, long-term objective of this research is the development of a tomographic reconstruction algorithm as a means to determine: (1) the depths and physical dimensions of discrete subsurface port-wine-stain (PWS) blood vessels in human skin; and (2) the initial space-dependent temperature increase in PWS blood vessels immediately following pulsed laser exposure. In this report, preliminary studies are described which demonstrate the potential application of IRT in the clinical management of PWS patients. |
| Databáze: | OpenAIRE |
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