Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: comparison of amastigote replication in adherent and nonadherent macrophages
| Autor: | C A Nacy, C L Diggs |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Leishmania tropica
Immunology Microbiology Mice Peritoneum parasitic diseases Cell Adhesion medicine Animals Ascitic Fluid Parasite hosting Macrophage Amastigote Cell adhesion Cells Cultured Leishmania biology Macrophages biology.organism_classification Infectious Diseases medicine.anatomical_structure Parasitology Intracellular Research Article |
| Zdroj: | Infection and Immunity. 34:310-313 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.34.1.310-313.1981 |
| Popis: | Intracellular replication of Leishmania tropica was assessed in mouse peritoneal macrophage cultures. L. tropica replicated poorly in macrophage monolayers: both the percentage of cells infected and the number of intracellular amastigotes decreased with time in culture. In contrast, nonadherent macrophages supported continuous replication of the parasite, and intracellular amastigotes increased more than 10-fold in these cultures over 8 days. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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