Polycystic ovary syndrome and obesity: clinical aspects and nutritional management
| Autor: | Evelyn Frias-Toral, Noemi Bautista-Litardo, Maria de los Angeles Carignano, Eloisa Garcia-Velasquez, Irene Alvarado-Aguilera, Dolores Rodriguez-Veintimilla |
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| Rok vydání: | 2021 |
| Předmět: |
Infertility
medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Disease Overweight Endocrinology Insulin resistance Weight loss Internal medicine Internal Medicine Medicine Humans Medical nutrition therapy Obesity business.industry medicine.disease Polycystic ovary Female medicine.symptom Insulin Resistance business Infertility Female Polycystic Ovary Syndrome |
| Zdroj: | Minerva endocrinology. 47(2) |
| ISSN: | 2724-6116 |
| Popis: | Introduction Polycystic Ovary Syndrome (PCOS) is a multifactorial endocrine and metabolic disorder characterized by androgen excess, oligo-anovulatory infertility, polycystic ovaries in ultrasound examination, insulin resistance, and cardiometabolic disorders, with overweight/obesity and visceral adiposity. This review aims to provide an overview of the clinical characteristics and nutritional therapy of PCOS and obesity. Methods The authors analyzed the updated and relevant publications found on Pubmed about clinical aspects and nutritional management of PCOS and obesity in studies done in animal and human models. Discussion It is crucial an early detection and intervention in PCOS patients to avoid the more challenging control of the onset of more impaired-health conditions that this pathology causes. It is presented evidence that clearly shows the close interaction among oxidative stress, low-grade inflammation, and PCOS. It is also analyzed the relevance of treating metabolic and nutritional correlations of PCOS with a complete therapeutic strategy that includes individualized medication, diet, and healthy habits. Conclusions By an integral approach and treatment that includes not only medications for PCOS symptoms, supplementation of minerals and vitamins to control PCOS complications but an antiinflammatory diet, nutritional education, exercise individualized program, lifestyle changes, it is possible to improve insulin resistance, sustained weight loss, ovulation rates, among other goals for the management of this disease. Further studies are needed to clarify mechanisms, beneficial effects, and doses of supplements and precise medication to determine the best combination of diets and exercise programs according to these patients' specific requirements. |
| Databáze: | OpenAIRE |
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